Aipulimong chem

Clinical trial: CBD (Cannabinol) can alleviate hand pain in osteoarthritis

  1. CBD significantly alleviates symptoms of hand arthritis

This study was completed by an Australian research team. Fifteen patients with hand osteoarthritis completed the experiment. Participants were asked to use gel containing 4% CBD three times a day on their most painful hands for four weeks. Through smartphone technology, researchers conducted a comprehensive evaluation of the pain level, hand function, and quality of life of participants, including indicators such as sleep, anxiety, muscle stiffness, and fatigue.

The results showed that participants’ pain scores, grip strength, fatigue, muscle stiffness and anxiety were significantly improved after using CBD gel. Especially the pain score, including current pain, average pain, and maximum pain, decreased by about 2 points (on a 0-10 scoring system), demonstrating significant analgesic effects.

In addition, there was a significant improvement in the grip strength of the treated hand, although self-reported hand function did not show significant improvement. In terms of quality of life, scores for fatigue, stiffness, and anxiety have all decreased, indicating an overall improvement in the patient’s quality of life.

2.CBD absorption and safety are good

Urine analysis showed that CBD and its metabolites could be detected in the bodies of all participants, but at low concentrations, indicating that CBD can be absorbed by the human body through transdermal means and also suggesting its potential safety.

3.CBD is equally effective for spinal stenosis

This study demonstrates for the first time the feasibility of transdermal application of CBD in alleviating pain in hand osteoarthritis and improving patient quality of life. However, researchers also emphasize that these preliminary findings still need to be validated in larger placebo-controlled randomized trials to confirm their efficacy.

It is worth noting that a previous study by Thomas Jefferson University in Philadelphia has linked transdermal delivery of CBD to reduced lower back and leg pain in patients with spinal stenosis. The researchers assessed the efficacy of twice daily use of CBD gel (15mgs) in 48 patients with spinal stenosis (mean age 75 years).

It was found that the patient’s pain score decreased by an average of nearly 2 points during the trial period (using an 11 point scoring system). In addition, the study also reported improvements in patient appetite, sleep quality, and overall quality of life. Meanwhile, patients receiving CBD treatment did not report any adverse side effects.

This study has opened up a new possible path for the treatment of hand osteoarthritis, and the potential value of CBD transdermal gel is worth further exploration. In the future, with the deepening of more scientific research, we are expected to see more CBD based products applied in clinical practice, providing more effective treatment plans for patients suffering from osteoarthritis.

Reference link:

https://norml.org/news/2024/05/30/clinical-trial-cbd-infused-gel-relieves-osteoarthritic-hand-pain/
https://pubmed.ncbi.nlm.nih.gov/38783008/
https://norml.org/news/2022/10/06/study-hemp-derived-cbd-gel-caps-effective-in-older-patients-with-spinal-stenosis/
https://www.cureus.com/articles/106551-the-use-of-cannabidiol-in-patients-with-low-back-pain-caused-by-lumbar-spinal-stenosis-an-observational-study#!/